7-氯-2,4-双(三氟甲基)-[1,8]萘啶合成路线 （共 4 条）
反应条件
trichlorophosphate in N,N-dimethyl-formamide T=100°C; 1.5 h; Cooling with ice;
参考文献
Organic Letters, , vol. 14, # 24 p. 6282 - 6285
反应条件
1: 95 percent / 85percent phosphoric acid / 12 h / 60 °C / sealed tube 2: 1) conc.H2SO4, sodium nitrite; 2) water / 1) RT, 12 h; 2) boiling steam bath, 30 min 3: 84 percent / phosphoryl chloride / 1 h / Heating View Scheme
参考文献
Journal of Heterocyclic Chemistry, , vol. 23, # 2 p. 501 - 504
反应条件
1: 95 percent / 85percent phosphoric acid / 12 h / 60 °C / sealed tube 2: 1) conc.H2SO4, sodium nitrite; 2) water / 1) RT, 12 h; 2) boiling steam bath, 30 min 3: 84 percent / phosphoryl chloride / 1 h / Heating View Scheme
参考文献
Journal of Heterocyclic Chemistry, , vol. 23, # 2 p. 501 - 504
反应条件
1: 1) conc.H2SO4, sodium nitrite; 2) water / 1) RT, 12 h; 2) boiling steam bath, 30 min 2: 84 percent / phosphoryl chloride / 1 h / Heating View Scheme
参考文献
Journal of Heterocyclic Chemistry, , vol. 23, # 2 p. 501 - 504
