6-甲基-3-氯甲基吡啶盐酸盐合成路线 (共 3 条)
反应条件
thionyl chloride in chloroform; toluene T=20 - 35°C; 1 h;
参考文献
Phan, Hieu Trung; Nguyen, Lan Mong; Azoulay, Raymond; Diep, Vinh Van; Eschenhof, Harald; Niesor, Eric Joseph; Bentzen, Craig Leigh; Ife, Robert John
Patent: US2005/124586 A1, 2005 ;
Location in patent: Page/Page column 7 ;
反应条件
1: sodium tetrahydroborate / methanol / 20 °C 2: thionyl chloride / toluene / 1 h / 65 °C View Scheme
参考文献
WO2012/82689 A1, ;
WO 2012/082689 A1
反应条件
sodium hydroxide in dichloromethane; water pH=7 - 8;
参考文献
Phan, Hieu Trung; Nguyen, Lan Mong; Azoulay, Raymond; Diep, Vinh Van; Eschenhof, Harald; Niesor, Eric Joseph; Bentzen, Craig Leigh; Ife, Robert John
Patent: US2005/124586 A1, 2005 ;
Location in patent: Page/Page column 7 ;