1,2,3,4-四氢苯并[4,5]呋喃[2,3-C]吡啶合成路线 （共 3 条）
反应条件
1: With hydrogenchloride in water 18 h; Heating / reflux; 2: With sodium hydrogencarbonate in water T=0°C;
参考文献
MIKANA THERAPEUTICS, INC.
Patent: WO2006/88949 A1, 2006 ;
Location in patent: Page/Page column 172-175 ;
反应条件
1: With formic acid T=20 - 50°C; Pictet-Spengler Cyclisation; 3 h; 2: With sodium hydroxide in dichloromethane; water
参考文献
WO2009/3003 A2, ;
Page/Page column 66-67 ;
WO 2009/003003 A2
