2,4-二氯-5-氟-3-硝基苯甲酸合成路线 （共 5 条）
反应条件
nitric acid in methanol; ice-water
反应条件
sulfuric acid; nitric acid
参考文献
Tetrahedron Letters, , vol. 50, # 21 p. 2525 - 2528
反应条件
sulfuric acid; nitric acid 1.) 55 deg C; 2.) 75 deg C, 3 h;
参考文献
Journal of Heterocyclic Chemistry, , vol. 25, p. 927 - 930
反应条件
1.1: 91 percent / thionylchloride / 1 h / Heating 2.1: Mg; ethanol; tetrachloromethane / toluene / 2 h / 70 °C 2.2: toluene / 0 - 20 °C 2.3: aq. sulfuric acid / 0 °C View Scheme
参考文献
Engler, Michael; Ruesing, Guido; Soergel, Fritz; Holzgrabe, Ulrike
Antimicrobial Agents and Chemotherapy, 1998 , vol. 42, # 5 p. 1151 - 1159
反应条件
thionyl chloride 1 h; Heating;
参考文献
Engler, Michael; Ruesing, Guido; Soergel, Fritz; Holzgrabe, Ulrike
Antimicrobial Agents and Chemotherapy, 1998 , vol. 42, # 5 p. 1151 - 1159
