咪唑[1,2-A]吡啶-6-甲腈合成路线 (共 5 条)
反应条件
1: in acetonitrile T=20°C; Reflux; 2: With sodium hydrogencarbonate in water pH=7;
参考文献
Laboratorios Almirall, S.A.
Patent: EP2202232 A1, 2010 ;
Location in patent: Page/Page column 55 ;
反应条件
1: in water; acetonitrile 20 h; Reflux; 2: With sodium hydrogencarbonate in water; acetonitrile pH=7;
参考文献
Almirall, S.A.
Patent: EP2397482 A1, 2011 ;
Location in patent: Page/Page column 33 ;
EP 2397482 A1
反应条件
pyridine; hydroxylamine-o-sulphonic acid in methanol T=20°C;
参考文献
US2012/245178 A1, ;
Page/Page column 20 ;
US 20120245178 A1
反应条件
1: N,N-dimethyl-formamide / 130 °C 2: hydroxylamine-o-sulphonic acid; pyridine / methanol / 20 °C View Scheme
参考文献
US2012/245178 A1, ;
US 20120245178 A1