4-氨基-2,2-二氟-1,3-苯并二恶茂合成路线 （共 5 条）
反应条件
potassium carbonate; palladium monocarbide in methanol; water
反应条件
potassium hydroxide; bromine in water
反应条件
LiNHOCH3; sec.-butyllithium in diethyl ether T=-15°C; 2 h;
参考文献
Schlosser, Manfred; Gorecka, Joanna; Castagnetti, Eva
European Journal of Organic Chemistry, 2003 , # 3 p. 452 - 462
反应条件
1.1: 68 percent / diethyl ether / 3 h / 25 °C 2.1: 84 percent / hydroxylamine hydrochloride; sodium acetate trihydrate / methanol / 0.5 h / Heating 3.1: phosphorus pentachloride / benzene / 0.25 h / Heating 3.2: 82 percent / hydrochloric acid / H2O; ethanol / 6 h / Heating View Scheme
参考文献
European Journal of Organic Chemistry, , # 3 p. 452 - 462
反应条件
1.1: 84 percent / hydroxylamine hydrochloride; sodium acetate trihydrate / methanol / 0.5 h / Heating 2.1: phosphorus pentachloride / benzene / 0.25 h / Heating 2.2: 82 percent / hydrochloric acid / H2O; ethanol / 6 h / Heating View Scheme
参考文献
European Journal of Organic Chemistry, , # 3 p. 452 - 462
