2,3-O-(1-甲基亚乙基)-beta-D-吡喃果糖1-氨基磺酸酯合成路线 （共 4 条）
反应条件
hydrogenchloride in tetrahydrofuran T=45°C; 3.5 h;
参考文献
Maryanoff, Bruce E.; Nortey, Samuel O.; Gardocki, Joseph F.; Shank, Richard P.; Dodgson, Susanna P.
Journal of Medicinal Chemistry, 1987 , vol. 30, # 5 p. 880 - 887
反应条件
1: 1.) NaH, 2.) sulfamoyl chloride / 1.) DMF, -4 deg C, 90 min, 2.) DMF, 0 deg C, 3.5 h 2: 31 percent / 3 N HCl / tetrahydrofuran / 3.5 h / 45 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 30, # 5 p. 880 - 887
参考文献
Journal of Medicinal Chemistry, , vol. 41, # 8 p. 1315 - 1343
反应条件
in tetrahydrofuran; CH2Cl2/EtOAc; benzene
参考文献
Ortho McNeil-Pharmaceutical, Inc.
Patent: US6495523 B1, 2002 ;
