[2-(异丙基氨基)苯基]甲醇合成路线 （共 6 条）
反应条件
sodium tetrahydroborate in ethanol; toluene
参考文献
Yamakawa; Matsukura; Nomura; Yoshioka; Masaki; Igata; Okabe
Chemical and Pharmaceutical Bulletin, 1991 , vol. 39, # 7 p. 1746 - 1752
反应条件
lithium aluminium tetrahydride in tetrahydrofuran T=0°C;
参考文献
THERAVANCE, INC.
Patent: US2006/100236 A1, 2006 ;
Location in patent: Page/Page column 21 ;
US 20060100236 A1
反应条件
1: 93 percent / aq. AcOH / 2 h / 0 - 20 °C 2: 79 percent / H2 / 5 percent Pd/C / methanol / 40 °C View Scheme
参考文献
Yamakawa; Matsukura; Nomura; Yoshioka; Masaki; Igata; Okabe
Chemical and Pharmaceutical Bulletin, 1991 , vol. 39, # 7 p. 1746 - 1752
反应条件
sodium hydroxide; sodium tetrahydroborate; sodium acetate in ethanol; acetic acid T=0 - 5°C; Alkylation; 1 h;
参考文献
Suzuki, Masaji; Kaneko, Toshie; Kamiyama, Hiroaki; Ohuchi, Yutaka; Yokomori, Sadakazu
Heterocycles, 2000 , vol. 53, # 11 p. 2471 - 2485
参考文献
Paal; Laudenheimer
Chemische Berichte, 1892 , vol. 25, p. 2979
参考文献
Paal; Laudenheimer
Chemische Berichte, 1892 , vol. 25, p. 2979
