阿德福韦合成路线

参考文献

European Journal of Medicinal Chemistry, , vol. 46, # 9 p. 4281 - 4288

参考文献

Reddy, K. Raja; Matelich, Michael C.; Ugarkar, Bheemarao G.; Gomez-Galeno, Jorge E.; DaRe, Jay; Ollis, Kristin; Sun, Zhili; Craigo, William; Colby, Timothy J.; Fujitaki, James M.; Boyer, Serge H.; Van Poelje, Paul D.; Erion, Mark D.
Journal of Medicinal Chemistry, 2008 , vol. 51, # 3 p. 666 - 676

106941-25-7阿德福韦

116384-53-3[[2-(6-氨基-9H-嘌呤-9-基)乙氧基]甲基]膦酸二乙酯

参考文献

Starrett, John E.; Tortolani, David R.; Russell, John; Hitchcock, Michael J. M.; Whiterock, Valerie; et al.
Journal of Medicinal Chemistry, 1994 , vol. 37, # 12 p. 1857 - 1864

18997-19-8特戊酸氯甲酯+

106941-25-7阿德福韦

142340-99-6阿德福韦酯

参考文献

WO2010/110506 A1, ;

Page/Page column 7 ;

参考文献

EP2330107 A2, ;

Page/Page column 6 ;

106941-25-7阿德福韦

142341-24-0

参考文献

Starrett, John E.; Tortolani, David R.; Russell, John; Hitchcock, Michael J. M.; Whiterock, Valerie; et al.
Journal of Medicinal Chemistry, 1994 , vol. 37, # 12 p. 1857 - 1864

106941-25-7阿德福韦

113884-65-4

参考文献

Holy, Antonin; Rosenberg, Ivan; Dvorakova, Hana
Collection of Czechoslovak Chemical Communications, 1989 , vol. 54, # 8 p. 2190 - 2210