hydrogenchloride; water in methanol T=50°C; 1 h;

selenium T=330 - 340°C;

1.1: N-ethyl-N,N-diisopropylamine / dichloromethane / 0 - 20 °C 2.1: n-butyllithium / tetrahydrofuran; hexane / 1 h / -78 °C 2.2: -78 - 20 °C 3.1: n-butyllithium / hexane; diethyl ether / 1 h / 0 - 20 °C / |Inert atmosphere 3.2: 1 h / 20 °C 4.1: hydrogenchloride; water / methanol / 1 h / 50 °C View Scheme

1.1: n-butyllithium / tetrahydrofuran; hexane / 1 h / -78 °C 1.2: -78 - 20 °C 2.1: n-butyllithium / hexane; diethyl ether / 1 h / 0 - 20 °C / |Inert atmosphere 2.2: 1 h / 20 °C 3.1: hydrogenchloride; water / methanol / 1 h / 50 °C View Scheme

1.1: n-butyllithium / hexane; diethyl ether / 1 h / 0 - 20 °C / |Inert atmosphere 1.2: 1 h / 20 °C 2.1: hydrogenchloride; water / methanol / 1 h / 50 °C View Scheme