丙烯腈合成路线 - 魔法化学

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AMBIT BIOSCIENCES CORPORATION; FARAONI, Raffaella; HADD, Michael, J.; HOLLADAY, Mark, W.; ROWBOTTOM, Martin; SETTI, Eduardo
Patent: WO2012/30944 A2, 2012 ;
Location in patent: Page/Page column 95-96 ;
WO 2012/030944 A2

104-87-0对甲基苯甲醛+

107-13-1丙烯腈

3528-45-81-[(4-甲氧基苯基)甲基]-1H-吡唑-5-胺

参考文献

Misra, Raj N.; Rawlins, David B.; Xiao, Hai-Yun; Shan, Weifang; Bursuker, Isia; Kellar, Kristin A.; Mulheron, Janet G.; Sack, John S.; Tokarski, John S.; Kimball, S. David; Webster, Kevin R.
Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 6 p. 1133 - 1136

100-52-7苯甲醛+

107-13-1丙烯腈

3528-51-61-苄基-1H-吡唑-5-胺

参考文献

GLAX0SMITHKLINE LLC; BURGESS, Joelle, Lorraine; JOHNSON, Neil, W.; KNIGHT, Steven, David; LAFRANCE, Louis, Vincent, III; MILLER, William, H.; NEWLANDER, Kenneth, Allen; ROMERIL, Stuart, Paul; ROUSE, Meagan, B.; SUAREZ, Dominic; TIAN, Xinrong; VERMA, Sharad, Kumar
Patent: WO2013/39988 A1, 2013 ;
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107-13-1丙烯腈+

3068-32-42,3,4,6-四乙酰氧基-alpha-D-吡喃糖溴化物

86563-28-2+

4098-06-0D-三乙酰半乳糖烯

参考文献

Spencer, Roxanne P.; Schwartz, Jeffrey
Journal of Organic Chemistry, 1997 , vol. 62, # 13 p. 4204 - 4205

107-13-1丙烯腈

35520-41-3反-3-(二甲氨基)丙烯腈+

62217-65-6+

1738-25-6二甲氨基丙腈

参考文献

Liebigs Annalen der Chemie, , # 7 p. 997 - 1015

6926-39-2+

107-13-1丙烯腈

35520-41-3反-3-(二甲氨基)丙烯腈

参考文献

Papa,A.J.
Journal of Organic Chemistry, 1966 , vol. 31, p. 1426 - 1430

5762-56-1三(二甲氨基)甲烷+

107-13-1丙烯腈

35520-41-3反-3-(二甲氨基)丙烯腈

参考文献

Schmetzer,J. et al.
Tetrahedron Letters, 1976 , p. 4061 - 4064

107-13-1丙烯腈

353-07-12-氰基乙基肼

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Osei-Twum, Emmanuel Y.; McCallion, Doug; Nazran, Avtar S.; Panicucci, Rick; Risbood, Prabhakar A.; Warkentin, John
Journal of Organic Chemistry, 1984 , vol. 49, # 2 p. 336 - 342

541-41-3+

107-13-1丙烯腈

353-07-12-氰基乙基肼

参考文献

Bayer Aktiengesellschaft
Patent: US3987168 A1, 1976 ;

参考文献

Hu, Chan-Ming; Qiu, Yao-Ling
Journal of Organic Chemistry, 1992 , vol. 57, # 12 p. 3339 - 3342