1: 4-[4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl]-phenol With sodium hydride in N,N-dimethyl-formamide; mineral oil
T=0°C; 0.166667 h;
2: chloromethyl methyl ether in N,N-dimethyl-formamide; mineral oil
1 h;
参考文献
TAKEDA PHARMACEUTICAL COMPANY LIMITED; RAKER, Joseph; TANIGUCHI, Takahiko; YOSHIKAWA, Masato; HASUI, Tomoaki; KUNITOMO, Jun
Patent: WO2012/18909 A1, 2012 ;
Location in patent: Page/Page column 165 ;
WO 2012/018909 A1
zinc(II) chloride in diethyl ether
T=23°C; 4 h; Yield given. Yields of byproduct given;
参考文献
Leets, K. V.; Shmidt, M. I.; Vyalimyae, T. K.; Kaal, T. A.
Journal of Organic Chemistry USSR (English Translation), 1984 , vol. 20, # 7 p. 1445
Zhurnal Organicheskoi Khimii, 1984 , vol. 20, # 7 p. 1588 - 1589
