1: 2-cyano-acetamide With sodium ethanolate in ethanol T=20°C; 0.133333 h; Inert atmosphere; 2: 2-Dimethylaminomethylen-acetessigsaeureethylester in ethanol T=20°C; 3: With acetic acid in ethanol
参考文献
ASTRAZENECA AB; BYLUND, Ruth; HOVDAL, Daniel; JOHANSSON, Johan; SELLEN, Mikael; ZETTERBERG, Fredrik
Patent: WO2010/5385 A1, 2010 ;
Location in patent: Page/Page column 77-78; 85-86 ;
WO 2010/005385 A1