2-氯-N,N-二甲基乙胺合成路线 （共 199 条）
反应条件
sodium methylate; chlorobenzene
参考文献
Ahn, Gang; Schifano-Faux, Nadege; Goossens, Jean-Francois; Baldeyrou, Brigitte; Couture, Axel; Grandclaudon, Pierre; Lansiaux, Amelie; Ryckebusch, Adina
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 8 p. 2259 - 2263
参考文献
VEB Deutsches Hydrierwerk
Patent: DE1046625 , 1957 ;
反应条件
in isopropyl alcohol
参考文献
Krapcho; Turk
Journal of medicinal chemistry, 1966 , vol. 9, # 6 p. 809 - 812
反应条件
sodium hydride 1.) DMF, 20 min, 2.) DMF, toluene, 85 deg C, 4 h; Yield given. Multistep reaction;
参考文献
Kimball; Floyd; Das; Hunt; Krapcho; Rovnyak; Duff; Lee; Moquin; Turk; Hedberg; Moreland; Brittain; McMullen; Normandin; Cucinotta
Journal of Medicinal Chemistry, 1992 , vol. 35, # 4 p. 780 - 793
参考文献
Journal of the American Chemical Society, , vol. 81, p. 2527,2529, 2530
Farmaco, , vol. 48, # 12 p. 1641 - 1648
反应条件
ethanol anschliessendes Behandeln mit wss. HCl;
参考文献
Diwag Chem. Fabr.
Patent: DE905738 , 1943 ;
参考文献
VEB Deutsches Hydrierwerk
Patent: DE1046625 , 1957 ;
参考文献
Jilek et al.
Chemicke Listy, 1949 , vol. 43, p. 56
Chem.Abstr., 1951 , p. 575
反应条件
potassium carbonate in N,N-dimethyl-formamide T=80°C; 72 h;
参考文献
Strohfeldt, Katja; Mueller-Bunz, Helge; Pampillon, Clara; Sweeney, Nigel J.; Tacke, Matthias
European Journal of Inorganic Chemistry, 2006 , # 22 p. 4621 - 4628
反应条件
potassium carbonate in ethanol Heating;
参考文献
van der Stelt,C. et al.
Arzneimittel Forschung, 1964 , vol. 14, p. 1053 - 1055
