2-氯-N,N-二甲基乙胺合成路线 (共 199 条)
反应条件
sodium amide; toluene
参考文献
Mossini; Maggiali; Morini; Impicciatore; Molina
Farmaco, Edizione Scientifica, 1984 , vol. 39, # 3 p. 189 - 199
参考文献
Sperber et al.
Journal of the American Chemical Society, 1949 , vol. 71, p. 887,889
参考文献
Huttrer et al.
Journal of the American Chemical Society, 1946 , vol. 68, p. 1999,2000
Full Text Show Details
Soc. Usines Chim. Rhone-Poulenc
Patent: DE880749 , 1943 ;
DRP/DRBP Org.Chem.
Full Text Show Details
Soc. Usines Chim. Rhone-Poulenc
Patent: US2502151 , 1946 ;
反应条件
potassium carbonate in ethyl acetate; acetone
参考文献
SCHERING AKTIENGESELLSCHAFT
Patent: WO2005/42505 A1, 2005 ;
Location in patent: Page/Page column 62 ;
WO 2005/042505 A1
参考文献
McMahon,R.E. et al.
J. Med. Chem., 1963 , vol. 6, p. 343 - 346
反应条件
potassium carbonate in water Heating;
参考文献
Remenar, Julius F.; Lucht, Brett L.; Collum, David B.
Journal of the American Chemical Society, 1997 , vol. 119, # 24 p. 5567 - 5572
反应条件
potassium carbonate in NMP (1-methyl-2-pyrrolidone) T=80°C;
参考文献
NOVARTIS AG
Patent: WO2009/87212 A2, 2009 ;
Location in patent: Page/Page column 114 ;
参考文献
Bristol-Myers Squibb Company
Patent: US6255496 B1, 2001 ;
参考文献
Moore; Vernsten
Journal of the American Chemical Society, 1956 , vol. 78, p. 5633,5634
参考文献
Fujii
Yakugaku Zasshi, 1957 , vol. 77, p. 359
Chem.Abstr., 1957 , p. 12103