N-重氮基氨基甲酸叔-丁基酯合成路线 （共 237 条）
反应条件
1: dimethylsulfoxide; diethyl ether / 2 h / Ambient temperature 2: aq. NaOH View Scheme
参考文献
Hansen, John B.; Langvad, Eyvind; Frandsen, Flemming; Buchardt, Ole
Journal of Medicinal Chemistry, 1983 , vol. 26, # 10 p. 1510 - 1514
反应条件
in diethyl ether; dimethyl sulfoxide 1 h; Ambient temperature;
参考文献
Hansen, J. B.; Nielsen, M. C.; Ehrbar, U.; Buchardt, O.
Synthesis, 1982 , # 5 p. 404 - 405
反应条件
1: 88.4 percent / 1 N aq. NaoH / dioxane / 48 h / 45 °C 2: Na, NH3(liq.) / 0.17 h / -50 °C 3: 61 percent / 4 N aq. NaOH / 2 h / 25 °C / pH 10-10.5 4: 79.5 percent / diethyl ether 5: 100 percent / H2 / 10percent Pd/C / methanol / 24 h View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 24, # 5 p. 567 - 572
反应条件
in dichloromethane 0.333333 h; Yield given;
参考文献
Journal of Organic Chemistry, , vol. 48, # 5 p. 661 - 665
反应条件
sodium hydroxide in 1,4-dioxane; water T=25°C; 6 h;
参考文献
Jones, David A.; Sawyer, Wilbur H.
Journal of Medicinal Chemistry, 1980 , vol. 23, # 6 p. 696 - 698
反应条件
sodium hydroxide in 1,4-dioxane 48 h; Ambient temperature;
参考文献
Vince; Lee; Narang; Shirota
Journal of Medicinal Chemistry, 1981 , vol. 24, # 12 p. 1511 - 1514
反应条件
triethylamine in 1,4-dioxane; water T=50°C; 15 h;
参考文献
Stille, J. K.; Becker Y.
Journal of Organic Chemistry, 1980 , vol. 45, # 11 p. 2139 - 2145
反应条件
triethylamine in 1,4-dioxane; water
参考文献
Gray,C.J.; Parker,R.C.
Tetrahedron, 1975 , vol. 31, p. 2940 - 2943
反应条件
triethylamine in 1,4-dioxane; water 24 h; Ambient temperature;
参考文献
Falch, Erik; Krogsgaard-Larsen, Povl
Journal of Medicinal Chemistry, 1981 , vol. 24, # 3 p. 285 - 289
