N-重氮基氨基甲酸叔-丁基酯合成路线 （共 237 条）
反应条件
1: 92 percent / diethyl ether
2: 75 percent / toluene / 17 h / Heating
3: LiMCPBA / CH2Cl2 / 2 h / -78 °C
4: 95 percent / benzyltrimethylammonium hydroxyde / 1.) MeOH, 30 min, 2.) CHCl3, -30 deg C, 1 h
View Scheme
参考文献
Vidal, Joelle; Guy, Laure; Sterin, Sebastien; Collet, Andre
Journal of Organic Chemistry, 1993 , vol. 58, # 18 p. 4791 - 4793
反应条件
sodium hydroxide in 1,4-dioxane
T=50°C; 4 h;
参考文献
Lipkowski, Andrzej W.; Flouret, George
Polish Journal of Chemistry, 1980 , vol. 54, # 11/12 p. 2225 - 2228
反应条件
2: (i) ClCO2iBu, (ii) /BRN= 605257/
View Scheme
参考文献
Bonora,G.M.; Toniolo,C.
Gazzetta Chimica Italiana, 1977 , vol. 107, p. 381 - 385
反应条件
triethylamine in 1,4-dioxane; water
参考文献
Eli Lilly and Company
Patent: US4319028 A1, 1982 ;
反应条件
triethylamine in dichloromethane; di-isopropyl ether; water
参考文献
Sankyo Company, Limited
Patent: US4699905 A1, 1987 ;
US 4699905 A
反应条件
magnesium oxide; triethylamine in water
参考文献
Neubert,K. et al.
Zeitschrift fuer Chemie (Stuttgart, Germany), 1978 , vol. 18, p. 255 - 256
反应条件
1: KHCO3 / H2O; dioxane
2: ethanol
View Scheme
参考文献
Andruszkiewicz,R. et al.
Polish Journal of Chemistry, 1978 , vol. 52, p. 1167 - 1172
反应条件
in diethyl ether; dimethyl sulfoxide
1 h; Ambient temperature; Yield given. Yields of byproduct given;
参考文献
Hansen, J. B.; Nielsen, M. C.; Ehrbar, U.; Buchardt, O.
Synthesis, 1982 , # 5 p. 404 - 405
反应条件
1: dimethylsulfoxide; diethyl ether / 2 h / Ambient temperature
2: aq. NaOH
View Scheme
参考文献
Hansen, John B.; Langvad, Eyvind; Frandsen, Flemming; Buchardt, Ole
Journal of Medicinal Chemistry, 1983 , vol. 26, # 10 p. 1510 - 1514
反应条件
in diethyl ether; dimethyl sulfoxide
1 h; Ambient temperature; Yield given. Yields of byproduct given;
参考文献
Hansen, J. B.; Nielsen, M. C.; Ehrbar, U.; Buchardt, O.
Synthesis, 1982 , # 5 p. 404 - 405
