N-重氮基氨基甲酸叔-丁基酯合成路线 （共 237 条）
反应条件
magnesium oxide in 1,4-dioxane; water
参考文献
Schroeder,E.; Klieger,E.
Justus Liebigs Annalen der Chemie, 1964 , vol. 673, p. 208 - 220
反应条件
pyridine; triethylamine Yield given. Yields of byproduct given;
参考文献
Turan; Bajusz
Acta Chimica Academiae Scientiarum Hungaricae, 1981 , vol. 107, # 1 p. 7 - 9
反应条件
1: 88.4 percent / 1 N aq. NaoH / dioxane / 48 h / 45 °C 2: Na, NH3(liq.) / 0.17 h / -50 °C 3: 61 percent / 4 N aq. NaOH / 2 h / 25 °C / pH 10-10.5 4: 79.5 percent / diethyl ether View Scheme
参考文献
Moore,S. et al.
Journal of Medicinal Chemistry, 1976 , vol. 19, p. 766 - 772
反应条件
1: (i), (ii) aq. NaOH, dioxane 2: DCC / ethyl acetate View Scheme
参考文献
Wuensch,E. et al.
Chemische Berichte, 1964 , vol. 97, p. 1819 - 1828
反应条件
triethylamine in 1,4-dioxane; water 48 h; Ambient temperature;
参考文献
Journal of Organic Chemistry, , vol. 46, # 9 p. 1868 - 1873
参考文献
Chiba, Katsumi; Mori, Miwako; Ban, Yoshio
Journal of the Chemical Society, Chemical Communications, 1980 , # 16 p. 770 - 772
参考文献
Bristol-Myers Company
Patent: US3985747 A1, 1976 ;
参考文献
Bristol-Myers Company
Patent: US4061862 A1, 1977 ;
反应条件
in dimethyl sulfoxide Ambient temperature;
参考文献
Hruby; Sawyer; Yang; Bregman; Hadley; Heward
Journal of Medicinal Chemistry, 1980 , vol. 23, # 12 p. 1432 - 1437
反应条件
(i) aq. HBr, AcOH, (ii) /BRN= 1363586/, Et3N, dioxane; Multistep reaction;
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 19, p. 1708 - 1713
