3,3-二甲基-1-丁酸合成路线 （共 132 条）
反应条件
1: SOCl2 View Scheme
参考文献
Homeyer; Whitmore; Wallingford
Journal of the American Chemical Society, 1933 , vol. 55, p. 4209,4212
反应条件
(i) ion-exchange resin <OH- form>, aq. NaOH, MeOH, (ii) /BRN= 505934/; Multistep reaction;
参考文献
Moore,G.G. et al.
Journal of Organic Chemistry, 1979 , vol. 44, p. 2425 - 2429
反应条件
bromine in methanol; water
反应条件
influense of solvent on the yield of inverted product; Product distribution;
参考文献
Kirmse, Wolfgang; Siegfried, Rainer
Journal of the American Chemical Society, 1983 , vol. 105, # 105 p. 950 - 956
反应条件
N,N,N',N',N'',N''-hexamethylphosphoric triamide; lithium diisopropyl amide 1.) 0 deg C, THF; 2.) 0 deg C, 2 h; Yield given. Multistep reaction;
参考文献
Atkinson, Robert S.; Tughan, Gary
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1987 , p. 2787 - 2796
反应条件
1: SOCl2 2: bromine View Scheme
参考文献
Homeyer; Whitmore; Wallingford
Journal of the American Chemical Society, 1933 , vol. 55, p. 4209,4212
反应条件
(i) SOCl2, (ii) Br2, I2, (iii) /BRN= 1718733/; Multistep reaction;
参考文献
Szabolcs; Kruppa; Sagi; Otvos
Journal of Labelled Compounds and Radiopharmaceuticals, 1978 , vol. 14, # 5 p. 713 - 726
反应条件
1: thionyl chloride / 1 h / Heating 2: Br2 / CCl4 / 3.5 h / Heating 3: CCl4; CH2Cl2 View Scheme
参考文献
Shimazu, Masako; Endo, Yasuyuki; Shudo, Koichi
Heterocycles, 1997 , vol. 45, # 4 p. 735 - 744
反应条件
lithium diisopropyl amide
参考文献
Angelaud, Remy; Landais, Yannick
Tetrahedron Letters, 1997 , vol. 38, # 2 p. 233 - 236
反应条件
1: SOCl2 View Scheme
参考文献
Duhamel,L. et al.
Bulletin de la Societe Chimique de France, 1970 , p. 1797 - 1804
