8-甲基-2-苯基-4-喹啉羧酸合成路线 （共 4 条）
反应条件
benzaldehyde in ethanol
反应条件
potassium hydroxide in ethanol; water Pfitzinger reaction; 18 h; Heating;
参考文献
Boa, Andrew N.; Canavan, Shane P.; Hirst, Paul R.; Ramsey, Christopher; Stead, Andrew M.W.; McConkey, Glenn A.
Bioorganic and Medicinal Chemistry, 2005 , vol. 13, # 6 p. 1945 - 1967
反应条件
in ethanol 3 h; Heating;
参考文献
Atwell; Baguley; Denny
Journal of Medicinal Chemistry, 1989 , vol. 32, # 2 p. 396 - 401
反应条件
1: 93 percent / Cu-powder / 280 - 290 °C 2: 34 percent / SeO2 / a) 180 to 190 deg C, b) 280 to 290 deg C, 2 min 3: 1.) 1,1'-carbonyldiimidazole, 3.) conc. HCl / 1.) DMF, 20 to 40 deg C, 20 min, 2.) 20 deg C, 15 min View Scheme
参考文献
Atwell; Baguley; Denny
Journal of Medicinal Chemistry, 1989 , vol. 32, # 2 p. 396 - 401
