反应条件
1.1: n-butyllithium / hexane; tetrahydrofuran / 1 h / -78 °C
1.2: 1.75 h / -78 °C
1.3: -78 - 25 °C
2.1: N-ethyl-N,N-diisopropylamine / tris-(dibenzylideneacetone)dipalladium(0) / 1,4-dioxane / 17 h / 110 °C / Inert atmosphere
View Scheme
参考文献
Berthel, Steven Joseph; Billedeau, Roland Joseph; Brotherton-Pleiss, Christine E.; Firooznia, Fariborz; Gabriel, Stephen Deems; Han, Xiaochun; Hilgenkamp, Ramona; Jaime-Figueroa, Saul; Kocer, Buelent; Lopez-Tapia, Francisco Javier; Lou, Yan; Orzechowski, Lucja; Owens, Timothy D.; Tan, Jenny; Wovkulich, Peter Michael
Patent: US2012/40949 A1, 2012 ;
US 20120040949 A1