1: 5-bromopyridin-2-yl amine With sodium hydride in N,N-dimethyl-formamide 0.5 h; Cooling with ice; 2: methyl iodide T=20°C; 24 h;
参考文献
Demont, Emmanuel Hubert; Garton, Neil Stuart; Gosmini, Romain Luc Marie; Hayhow, Thomas George Christopher; Seal, Jonathan; Wilson, David Matthew; Woodrow, Michael David
Patent: US2012/208798 A1, 2012 ;
Location in patent: Page/Page column 16 ;