2-氨基-5-氯吡啶合成路线

PTC THERAPEUTICS, INC.; F. HOFFMANN-LA ROCHE AG; WOLL, Matthew G.; CHEN, Guangming; CHOI, Soongyu; DAKKA, Amal; HUANG, Song; KARP, Gary Mitchell; LEE, Chang-Sun; LI, Chunshi; NARASIMHAN, Jana; NARYSHKIN, Nikolai; PAUSHKIN, Sergey; QI, Hongyan; TURPOFF, Anthony A.; WEETALL, Marla L.; WELCH, Ellen; YANG, Tianle; ZHANG, Nanjing; ZHANG, Xiaoyan; ZHAO, Xin; PINARD, Emmanuel; RATNI, Hasane
Patent: WO2013/101974 A1, 2013 ;
Location in patent: Paragraph 00763; 00764 ;

1072-98-62-氨基-5-氯吡啶+

84911-18-22-溴-3-氧代丁酸乙酯

59128-02-8(6-氯咪唑并[1,2-a]吡啶-2-基)-乙酸乙酯

参考文献

Misra, Anju P.; Raj; Bhaduri
Synthetic Communications, 1999 , vol. 29, # 18 p. 3227 - 3236

1072-98-62-氨基-5-氯吡啶

330942-05-7贝曲西班

参考文献

WO2011/84519 A1, ;

1072-98-62-氨基-5-氯吡啶+

6160-65-2N,N'-硫羰基二咪唑

149488-61-9

参考文献

Venkatachalam, Taracad K; Sudbeck, Elise A; Uckun, Fatih M
Tetrahedron Letters, 2001 , vol. 42, # 38 p. 6629 - 6632
Title/Abstract Full Text View citing articles Show Details
Venkatachalam, Taracad K.; Qazi, Sanjive; Samuel, Peter; Uckun, Fatih M.
Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 3 p. 485 - 488
Title/Abstract Full Text View citing articles Show Details
Venkatachalam; Qazi; Samuel; Uckun
Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 6 p. 1095 - 1105

1072-98-62-氨基-5-氯吡啶

4214-79-35-氯-2-羟基吡啶

参考文献

Raghoottama, P. S.; Soundararajan, S.; Ramakrishna, J.
Journal of Molecular Structure, 1987 , vol. 157, p. 371 - 384