甲基(2-氧代乙基)氨基甲酸苄酯合成路线 （共 4 条）
反应条件
hydrogenchloride; diisopentylamine; sulfur trioxide pyridine complex in dichloromethane; dimethyl sulfoxide T=-110 - -10°C; 1.25 h;
参考文献
THERAVANCE, INC.
Patent: WO2004/89892 A2, 2004 ;
Location in patent: Page 90 ;
WO 2004/089892 A2
反应条件
1: With camphor-10-sulfonic acid 15 h; Heating; 2: With diisobutylaluminium hydride in hexane; dichloromethane T=-78°C; 2 h;
参考文献
Tietze, Lutz F.
Angewandte Chemie - International Edition, 2001 , vol. 40, # 5 p. 903 - 905
反应条件
1.1: aq. NaOH / 15 h / 20 °C 2.1: ROH; camphor sulfonic acid / 15 h / Heating 2.2: DIBAL-H / hexane; CH2Cl2 / 2 h / -78 °C View Scheme
参考文献
Martin; Davidsen; Puckette
Journal of Organic Chemistry, 1987 , vol. 52, # 10 p. 1962 - 1972
反应条件
hydrogenchloride; water T=22°C; 18 h; Product distribution / selectivity;
参考文献
COLSON, Pierre-Jean
Patent: US2012/16130 A1, 2012 ;
Location in patent: Page/Page column 9 ;
