2,6-di-tert-butyl-4-methyl-phenol in diphenylether T=200°C; 18 h;

lithium diisopropyl amide in hexane 1) 0 deg C, 15 min, 2) 0 deg C, 2 h; r.t., 1 h;

1: 99 percent / 1) lithium diisopropylamide / hexane / 1) hexane, 0 deg C, 30 min, 2) 0 deg C, 30 min 2: 33 percent / pyridine, phenyl dichlorophosphate / 1,2-dimethoxy-ethane / 18 h / Ambient temperature 3: 46 percent / diphenyl ether; various solvent(s) / 18 h View Scheme