反应条件
1: 1) N-chlorosuccinimide, AgNO3; 2) NaBH4 / 1) CH3CN, ether, H2O, 10 min; 2) CH3CN, ether, 1.5 h
2: pyridine / 0 deg C , 0.5 h then in refrigerator overnight
3: 0.126 g / ethanol; H2O; diethyl ether / 10 h / Ambient temperature
4: 1) 3N NaOH, 30percent H2O2; 2) conc. HCl / 1) ethanol, 90 deg C, 14 h; 2) pH = 3, overnight
View Scheme
参考文献
Frye, Stephen V.; Eliel, Ernest L.
Tetrahedron Letters, 1986 , vol. 27, # 28 p. 3223 - 3226
