2-甲氧基-3-(三氟甲基)苯硼酸合成路线 （共 2 条）
反应条件
1: With n-butyllithium in tetrahydrofuran; hexane T=20°C; 1 h; 2: With tri-isopropoxy-borane in tetrahydrofuran; hexane T=-78 - 20°C; 16.5 h; 3: With hydrogenchloride; water in tetrahydrofuran; hexane
参考文献
Takeda Pharmaceutical Company Limited
Patent: EP2295406 A1, 2011 ;
Location in patent: Page/Page column 71 ;
反应条件
1: 2-methoxybenzotrifluoride With n-butyllithium in tetrahydrofuran; hexane T=20°C; 1 h; 2: tri-isopropoxy-borane in tetrahydrofuran; hexane T=-78 - 20°C; 16.5 h; 3: hydrogenchloride; water in tetrahydrofuran; hexane
参考文献
Kasai, Shizuo; Kamaura, Masahiro; Cho, Nobuo
Patent: US2011/251187 A1, 2011 ;
Location in patent: Page/Page column 51 ;
