N-[2-[2-(二甲基氨基)乙氧基]-4-(1H-吡唑-4-基)苯基]-2,3-二氢-1,4-苯并二恶烷-2-甲酰胺合成路线 (共 1 条)
反应条件
tetrakis(triphenylphosphine) palladium(0); potassium carbonate in 1,4-dioxane; water T=90 - 100°C; Suzuki coupling; 4 h; Inert atmosphere;
参考文献
Feng, Yangbo; Yin, Yan; Weiser, Amiee; Griffin, Evelyn; Cameron, Michael D.; Lin, Li; Ruiz, Claudia; Schuerer, Stephan C.; Inoue, Toshihiro; Rao, P. Vasanth; Schroeter, Thomas; LoGrasso, Philip
Journal of Medicinal Chemistry, 2008 , vol. 51, # 21 p. 6642 - 6645