4,4-二甲基-2-环己基-1-酮合成路线 （共 63 条）
反应条件
in acetonitrile Irradiation; Quantum yield;
参考文献
Cruciani, Giuliano; Margaretha, Paul
Helvetica Chimica Acta, 1990 , vol. 73, # 4 p. 890 - 895
反应条件
in cyclohexane; butan-1-ol T=6°C; Irradiation; Further byproducts given;
参考文献
Tetrahedron, , vol. 46, # 15 p. 5383 - 5388
反应条件
sodium tetrahydroborate; cobalt(II) chloride in water T=30°C; Reduction; 1 h;
参考文献
Aramini, Andrea; Brinchi, Lucia; Germani, Raimondo; Savelli, Gianfranco
European Journal of Organic Chemistry, 2000 , # 9 p. 1793 - 1797
反应条件
sodium tetrahydroborate; Nd(EBAB)Cl3 in methanol 1 h; Ambient temperatureother reagents: Ce(EBAB)Cl3, Pr(EBAB)Cl3, Yb(PBAB)Cl3,; Product distribution;
参考文献
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, , vol. 35, # 5 p. 484 - 486
反应条件
lithium aluminium tetrahydride; 4,7,13,18-tetraoxa-1,10-diazabicyclo[8.5.5]eicosane in tetrahydrofuran 1 h; Ambient temperature; Yield given. Yields of byproduct given;
参考文献
Aramini, Andrea; Brinchi, Lucia; Germani, Raimondo; Savelli, Gianfranco
European Journal of Organic Chemistry, 2000 , # 9 p. 1793 - 1797
反应条件
sodium amide Title compound not separated from byproducts;
参考文献
Schmueser, Wolfgang; Voss, Juergen
Journal of Chemical Research, Miniprint, 1980 , # 8 p. 3361 - 3386
反应条件
1: palladium monocarbide / ethyl acetate 2: hydroxylamine hydrochloride; sodium carbonate / ethanol; water 3: hydrogenchloride / diethyl ether; ethanol; water View Scheme
参考文献
Smithkline Beecham Corporation
Patent: US2011/124559 A1, 2011 ;
参考文献
Dauben,W.G.; Spitzer,W.A.
Journal of the American Chemical Society, 1968 , vol. 90, p. 802
反应条件
1: diethyl ether / -78 - 20 °C
2: pyridinium chlorochromate / dichloromethane / 18 h / 20 °C
View Scheme
参考文献
BIKAM PHARMACEUTICALS, INC.; GARVEY, David, S.; GREENWOOD, Jeremy, R.; FRYE, Leah, L.
Patent: WO2013/82000 A1, 2013 ;
反应条件
(i), (ii) Py*HClCrO3; Multistep reaction;
参考文献
Dauben,W.G.; Michno,D.M.
Journal of Organic Chemistry, 1977 , vol. 42, # 4 p. 682 - 685
