[4-氨基-2-(甲基氨基)-1,3-噻唑-5-基](苯基)甲酮合成路线 (共 2 条)
反应条件
1: Carbamonitrile; isothiocyanatomethane With potassium tert-butylate in tetrahydrofuran T=20°C; 0.25 h; 2: α-bromoacetophenone in tetrahydrofuran T=20°C;
参考文献
Journal of Medicinal Chemistry, , vol. 56, # 10 p. 3768 - 3782
反应条件
1: acetone; ethanol / 1 h / Ambient temperature 2: triethylamine / acetone; ethanol / 60 deg C; r.t., 1 h View Scheme
参考文献
Synthesis, , # 5 p. 353 - 355