吡咯并[1,2-F]嘧啶-3-甲酸乙酯合成路线 （共 4 条）
反应条件
1,8-diazabicyclo[5.4.0]undec-7-ene in tetrahydrofuran T=20°C;
参考文献
Rogers, Bruce N.; Piotrowski, David W.; Walker, Daniel Patrick; Jacobsen, Eric Jon; Acker, Brad A.; Wishka, Donn G.; Groppi JR., Vincent E.
Patent: US2003/236264 A1, 2003 ;
Location in patent: Page 49 ;
反应条件
1,8-diazabicyclo[5.4.0]undec-7-ene in tetrahydrofuran T=20°C; Cycloaddition; 5 h;
参考文献
Minguez, Jose M.; Vaquero, Juan J.; Alvarez-Builla, Julio; Castano, Obis; Andres, Jose L.
Journal of Organic Chemistry, 1999 , vol. 64, # 21 p. 7788 - 7801
反应条件
trifluoroacetic acid in acetic acid room temp., 15 h, then reflux, 20 min;
参考文献
Biere, Helmut; Russe, Rolf
Liebigs Annalen der Chemie, 1987 , p. 491 - 494
反应条件
trifluoroacetic acid AcOH/CH2Cl2, room temp., 48 h, then after evaporation CH2Cl2, 150 deg C,1 h;
参考文献
Liebigs Annalen der Chemie, , p. 491 - 494
