3,3-四亚甲基戊二酰亚胺合成路线 （共 15 条）
反应条件
18-crown-6 ether; potassium carbonate in toluene T=111°C; 24 h; Inert atmosphere;
参考文献
Jaronczyk, Malgorzata; Wolosewicz, Karol; Gabrielsen, Mari; Nowak, Gabriel; Kufareva, Irina; Mazurek, Aleksander P.; Ravna, Aina W.; Abagyan, Ruben; Bojarski, Andrzej J.; Sylte, Ingebrigt; Chilmonczyk, Zdzislaw
European Journal of Medicinal Chemistry, 2012 , vol. 49, p. 200 - 210
参考文献
Mead Johnson and Company
Patent: US4320131 A1, 1982 ;
反应条件
sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate; potassium carbonate in benzene
3 h; Heating;
参考文献
Cybulski, Jacek; Chilmonczyk, Zdzislaw; Glice, Magdalena; Cybulski, Marcin; Bajdor, Krzysztof; Les, Andrzej
Journal of Molecular Structure, 1997 , vol. 404, # 1-2 p. 221 - 234
参考文献
Mead Johnson and Company
Patent: US4581357 A1, 1986 ;
反应条件
18-crown-6 ether; potassium carbonate in toluene
22 h; Heating;
参考文献
Yevich, Joseph P.; New, James S.; Smith, David W.; Lobeck, Walter G.; Catt, John D.; et al.
Journal of Medicinal Chemistry, 1986 , vol. 29, # 3 p. 359 - 369
