6-[4-(6-氧代-1H-哒嗪-3-基)苯基]-2H-哒嗪-3-酮合成路线 （共 5 条）
反应条件
sodium hydroxide; m-nitrobenzene sulfonic acid sodium salt in water Heating;
参考文献
Coates, William J.; Prain, H. Douglas; Reeves, Martin L.; Warrington, Brian H.
Journal of Medicinal Chemistry, 1990 , vol. 33, # 6 p. 1735 - 1741
反应条件
in sodium hydroxide; water
参考文献
Smith Kline and French Laboratories Limited
Patent: US4904664 A1, 1990 ;
反应条件
1: conc. aq. HCl / ethanol / 3 h / Heating 2: acetic acid / H2O / 3 h / 80 °C 3: conc. aq. HCl, acetic acid / 2 h / Heating 4: hydrazine hydrate / H2O / 4 h / Heating 5: 72 percent / sodium m-nitrobenzene sulphonate, NaOH / H2O / Heating View Scheme
参考文献
Coates, William J.; Prain, H. Douglas; Reeves, Martin L.; Warrington, Brian H.
Journal of Medicinal Chemistry, 1990 , vol. 33, # 6 p. 1735 - 1741
反应条件
1: conc. aq. HCl, acetic acid / 2 h / Heating 2: hydrazine hydrate / H2O / 4 h / Heating 3: 72 percent / sodium m-nitrobenzene sulphonate, NaOH / H2O / Heating View Scheme
参考文献
Coates, William J.; Prain, H. Douglas; Reeves, Martin L.; Warrington, Brian H.
Journal of Medicinal Chemistry, 1990 , vol. 33, # 6 p. 1735 - 1741
反应条件
1: hydrazine hydrate / H2O / 4 h / Heating 2: 72 percent / sodium m-nitrobenzene sulphonate, NaOH / H2O / Heating View Scheme
参考文献
Coates, William J.; Prain, H. Douglas; Reeves, Martin L.; Warrington, Brian H.
Journal of Medicinal Chemistry, 1990 , vol. 33, # 6 p. 1735 - 1741
