5-Boc-1-苯基-1,4,6,7-四氢吡唑并[4,3-c]吡啶合成路线 (共 3 条)
反应条件
1: With sodium carbonate; acetic acid in methanol; water; ethyl acetate T=20°C; 1 h; 2: With sodium hydrogencarbonate in methanol; water
参考文献
Bristol-Myers Squibb Company
Patent: US2008/275052 A1, 2008 ;
Location in patent: Page/Page column 32 ;
US 20080275052 A1
反应条件
in methanol 3 h; Reflux;
参考文献
US2012/245149 A1, ;
Page/Page column 13 ;
反应条件
1: Reflux 2: methanol / 3 h / Reflux View Scheme