2-(4-甲氧基苯基)-2-氧代乙醛合成路线 （共 34 条）
反应条件
bei der Ozonspaltung;
参考文献
Weygand
Justus Liebigs Annalen der Chemie, 1927 , vol. 459, p. 112
Justus Liebigs Annalen der Chemie, 1929 , vol. 472, p. 178
反应条件
toluene-4-sulfonic acid in methanol Heating; Further byproducts given;
参考文献
Tetrahedron, , vol. 62, # 47 p. 10900 - 10906
反应条件
1: benzenecarboximidamide hydrochloride With sodium sulfate; hydrazine in methanol T=0°C; 2 h; 2: 2-(4-methoxyphenyl)-2-oxoacetaldehyde in methanol T=20°C; 24 h;
参考文献
Ernd, Michael; Heuschmann, Manfred; Zipse, Hendrik
Helvetica Chimica Acta, 2005 , vol. 88, # 6 p. 1491 - 1518
反应条件
1: in tetrahydrofuran; methanol T=0°C; 0.166667 h; 2: With sodium tetrahydroborate in tetrahydrofuran; methanol T=0°C;
参考文献
MITSUBISHI PHARMA CORPORATION; SANOFI-SYNTHELABO
Patent: WO2004/85408 A1, 2004 ;
Location in patent: Page 262-263 ;
WO 2004/085408 A1
反应条件
in ethanol; water pH=9; 1 h; Alkaline aqueous solutionHeating / reflux;
参考文献
Albert Waer, Mark Jozef; Herdewijn, Piet Andre Maurits Maria; Pfleiderer, Wolfgang Eugen
Patent: US2004/77859 A1, 2004 ;
Location in patent: Page 26 ;
反应条件
sodium acetate in acetic acid
参考文献
Massarani; Nardi; Pozzi; Degen
Journal of medicinal chemistry, 1970 , vol. 13, # 1 p. 157 - 159
反应条件
1: acetic acid; concentrated sulfuric acid 2: toluene; PCl5 View Scheme
参考文献
Sisido et al.
Journal of the American Chemical Society, 1955 , vol. 77, p. 6580
参考文献
Meester, Johan W. G. De; Plas, Henk C. van der; Middelhoven, Wouter J.
Journal of Heterocyclic Chemistry, 1987 , vol. 24, p. 441 - 451
反应条件
hydrogenchloride; acetone-oxime in methanol; water
T=50°C; 2 h; pH 4;
参考文献
Meester, Johan W. G. De; Plas, Henk C. van der; Middelhoven, Wouter J.
Journal of Heterocyclic Chemistry, 1987 , vol. 24, p. 441 - 451
反应条件
1-amino-2-oxo-4,6-diphenylpyridine in toluene
T=110°C; 6 h;
参考文献
Alajarin, M.; Fresneda, P. M.; Molina, P.
Synthesis, 1980 , # 10 p. 844 - 845
