1: acetic anhydride / 0.25 h / Ambient temperature 2: 30percent aq. H2O2, 10percent aq. NaOH / acetone / 0.5 h / Ambient temperature 3: 1.) NaH / 1.) DMF, RT, 5 min, 2.) DMF, 50 deg C, 17 h 4: 21 percent / tetrahydrofuran; diethyl ether / 1 h / Ambient temperature View Scheme

in tetrahydrofuran; diethyl ether 1 h; Ambient temperature;