4-(2-噻吩基)苯甲醛合成路线 （共 12 条）
反应条件
tetrakis(triphenylphosphine) palladium(0); cesium fluoride in ethylene glycol dimethyl ether Suzuki coupling; 20 h; Heating;
参考文献
Weber, Dirk; Berger, Claudia; Eickelmann, Peter; Antel, Jochen; Kessler, Horst
Journal of Medicinal Chemistry, 2003 , vol. 46, # 10 p. 1918 - 1930
反应条件
1: With palladium diacetate; xantphos in N-dodecane; butan-1-ol T=25°C; Suzuki-Miyaura Coupling; 1 h; Inert atmosphereGlovebox; 2: With cesium hydroxide monohydrate in N-dodecane; water; butan-1-ol T=80°C; Suzuki-Miyaura Coupling; 4 h; Inert atmosphereGlovebox;
参考文献
Yang, Junfeng; Liu, Sijia; Zheng, Jian-Feng; Zhou, Jianrong
European Journal of Organic Chemistry, 2012 , # 31 p. 6248 - 6259,12
Title/Abstract Full Text Show Details
Yang, Junfeng; Liu, Sijia; Zheng, Jian-Feng; Zhou, Jianrong
European Journal of Organic Chemistry, 2012 , # 31 p. 6248 - 6259
反应条件
palladium diacetate; potassium carbonate; tri-cyclo-hexyl-phosphine; 2,2,2-trimethylacetic acid in N,N-dimethyl-formamide T=180°C; 0.166667 h; Inert atmosphereMicrowave irradiation;
参考文献
Baghbanzadeh, Mostafa; Pilger, Christian; Oliver Kappe
Journal of Organic Chemistry, 2011 , vol. 76, # 19 p. 8138 - 8142
反应条件
manganese(IV) oxide in chloroform 1 h; Heating;
参考文献
Tanaka, Akira; Terasawa, Takeshi; Hagihara, Hiroyuki; Sakuma, Yuri; Ishibe, Noriko; Sawada, Masae; Takasugi, Hisashi; Tanaka, Hirokazu
Journal of Medicinal Chemistry, 1998 , vol. 41, # 13 p. 2390 - 2410
反应条件
potassium acetate in thiophene; isobutyramide; water
参考文献
US5849911 A1, ;
US 5849911 A
反应条件
palladium diacetate T=100°C; Stille cross-coupling; 15 h; Ionic liquid;
参考文献
Louaisil, Nicolas; Pham, Phuoc Dien; Boeda, Fabien; Faye, Djibril; Castanet, Anne-Sophie; Legoupy, Stephanie
European Journal of Organic Chemistry, 2011 , # 1 p. 143 - 149
反应条件
tris-(dibenzylideneacetone)dipalladium(0); triphenyl-arsane in toluene Stille Cross Coupling; 20 h; Inert atmosphereReflux;
参考文献
Scrascia, Angela; De Marco, Luisa; Laricchia, Savio; Picca, Rosaria Anna; Carlucci, Claudia; Fabiano, Eduardo; Capodilupo, Agostina Lina; Della Sala, Fabio; Gigli, Giuseppe; Ciccarella, Giuseppe
Journal of Materials Chemistry A, 2013 , vol. 1, # 38 p. 11909 - 11921
反应条件
potassium carbonate in ethanol; water T=50°C; Suzuki coupling;
参考文献
European Journal of Organic Chemistry, , # 13 p. 2635 - 2642
反应条件
manganese triacetate Heating;
参考文献
Demir, Ayhan S.; Reis, Oemer; Emrullahoglu, Mustafa
Journal of Organic Chemistry, 2003 , vol. 68, # 2 p. 578 - 580
反应条件
1: 2-Iodothiophene With copper; zinc in N,N-dimethyl-formamide T=60°C; 0.05 h; 2: 4-bromo-benzaldehyde With bis-triphenylphosphine-palladium(II) chloride in N,N-dimethyl-formamide T=120°C; Negishi cross-coupling reaction; 0.0833333 h; Further stages.;
参考文献
Tetrahedron Letters, , vol. 45, # 20 p. 3909 - 3912
