1: meta-hydroxybenzaldehyde With di-isopropyl azodicarboxylate; triphenylphosphine in tetrahydrofuran
T=20°C; 0.25 h;
2: 2-(dimethylamino)-ethanol in tetrahydrofuran
T=20°C; 24 h;
参考文献
CEPHALON, INC.; BRESLIN, Henry J.; CURRY, Matthew A.; GINGRICH, Diane E.; LEARN, Keith S.; OTT, Gregory R.; WAGNER, Jason C.
Patent: WO2013/116291 A1, 2013 ;
Location in patent: Page/Page column 231 ;