1: With tri-n-butyltin methoxide; tris-(dibenzylideneacetone)dipalladium(0); N-[2'-(dicyclohexylphosphino)-1,1'-biphenyl-2-yl]-N,N-dimethylamine in toluene
16 h; Heating / reflux;
2: With water in toluene
参考文献
NOVARTIS AG
Patent: WO2008/52733 A1, 2008 ;
Location in patent: Page/Page column 60 ;
WO 2008/052733 A1