反应条件
1: malonic acid dimethyl ester With 2,2,6,6-tetramethyl-piperidine; n-butyllithium in tetrahydrofuran T=-78 - 20°C; 0.5 h; 2: 2-bromo-1,4-dimethoxybenzene in tetrahydrofuran T=-78°C; 2.75 h; 3: With ammonium chloride in tetrahydrofuran; water
参考文献
Sloman, David L.; Mitasev, Branko; Scully, Stephen S.; Beutler, John A.; Porco Jr., John A.
Angewandte Chemie - International Edition, 2011 , vol. 50, # 11 p. 2511 - 2515