4,6-二甲基-2-羟基嘧啶合成路线 （共 34 条）
参考文献
Angerstein
Chemische Berichte, 1901 , vol. 34, p. 3956
反应条件
in N-methyl-acetamide
参考文献
Shell Research Limited
Patent: US5139563 A1, 1992 ;
反应条件
potassium carbonate
1) acetonitrile, boiling, 45 min; 2) acetonitrile, boiling, 1 h; Yield given. Multistep reaction;
参考文献
Gefenas, V. I.; Vainilavichyus, P. I.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1984 , vol. 20, # 10 p. 1185 - 1186
Khimiya Geterotsiklicheskikh Soedinenii, 1984 , vol. 20, # 10 p. 1429 - 1430
反应条件
1: 82 percent / TEA / CH2Cl2 / 10 h / 0 °C
2: 1.) ZnBr2, 2.) Pd(PPh3)4 / 1.) THF, -78 deg C, 1 h, 2.) THF, 50 deg C, 2 h
View Scheme
参考文献
Sandosham, Jessie; Undheim, Kjell
Heterocycles, 1994 , vol. 37, # 1 p. 501 - 514
