反应条件
1.1: triethylamine / 1-methyl-pyrrolidin-2-one / 1.5 h / 90 °C / Inert atmosphere
2.1: sodium dithionite / ethanol; dimethyl sulfoxide / 2.5 h / 90 °C / Inert atmosphere
3.1: lithium hydroxide hydrate / tetrahydrofuran; methanol; water / 1 h / 30 °C / Inert atmosphere
3.2: 0 °C / pH 4 / Inert atmosphere
View Scheme
参考文献
Oda, Shinichi; Shimizu, Hideki; Aoyama, Yasunori; Ueki, Tatsuo; Shimizu, Sumio; Osato, Hiroshi; Takeuchi, Yoshiyuki
Organic Process Research and Development, 2012 , vol. 16, # 1 p. 96 - 101