(7S,13E,16S,18R,19E,21R)-7,18,21-三羟基-16,18-二甲基-10-苯基-(11)松胞素-5,13,19-三烯-1-酮合成路线 （共 4 条）
→
108050-26-6(7S,13E,16S,18R,19E,21R)-7,18,21-三羟基-16,18-二甲基-10-苯基-(11)松胞素-5,13,19-三烯-1-酮
反应条件
potassium hydroxide in methanol T=20°C; 4 h; Yield given;
参考文献
Tomioka; Izawa; Koyama; Natori
Chemical and Pharmaceutical Bulletin, 1987 , vol. 35, # 2 p. 902 - 905
→
108050-26-6(7S,13E,16S,18R,19E,21R)-7,18,21-三羟基-16,18-二甲基-10-苯基-(11)松胞素-5,13,19-三烯-1-酮
反应条件
1: H2SO4 / dimethylsulfoxide 2: 5 percent KOH View Scheme
参考文献
Izawa; Hirose; Shimizu; Koyama; Natori
Tetrahedron, 1989 , vol. 45, # 8 p. 2323 - 2335
→
108050-26-6(7S,13E,16S,18R,19E,21R)-7,18,21-三羟基-16,18-二甲基-10-苯基-(11)松胞素-5,13,19-三烯-1-酮
反应条件
1: pyridine 2: H2SO4 / dimethylsulfoxide 3: 5 percent KOH View Scheme
参考文献
Izawa; Hirose; Shimizu; Koyama; Natori
Tetrahedron, 1989 , vol. 45, # 8 p. 2323 - 2335
→
108050-26-6(7S,13E,16S,18R,19E,21R)-7,18,21-三羟基-16,18-二甲基-10-苯基-(11)松胞素-5,13,19-三烯-1-酮
反应条件
acetic acid T=45°C; 0.666667 h; Yield given. Yields of byproduct given;
参考文献
Izawa; Hirose; Shimizu; Koyama; Natori
Tetrahedron, 1989 , vol. 45, # 8 p. 2323 - 2335
