2-羟基甲基-6-甲基-异烟腈合成路线 （共 5 条）
反应条件
pyridine; trifluoroacetic anhydride in dichloromethane T=0 - 20°C; 1 h;
参考文献
Bolli, Martin; Lescop, Cyrille; Mathys, Boris; Mueller, Claus; Nayler, Oliver; Steiner, Beat; Velker, Jorg
Patent: US2011/212998 A1, 2011 ;
Location in patent: Page/Page column 33 ;
US 20110212998 A1
参考文献
NIPPON SODA CO., LTD.
Patent: EP1362850 A1, 2003 ;
Location in patent: Page/Page column 32 ;
反应条件
1.1: sulfuric acid / 72 h / Reflux 1.2: 48 h / 65 °C 2.1: ammonia / methanol / 24 h / 70 °C / sealed 3.1: trifluoroacetic anhydride; pyridine / dichloromethane / 0 - 20 °C View Scheme
参考文献
Bolli, Martin; Lescop, Cyrille; Mathys, Boris; Mueller, Claus; Nayler, Oliver; Steiner, Beat; Velker, Jorg
Patent: US2011/212998 A1, 2011 ;
US 20110212998 A1
反应条件
1: ammonia / methanol / 24 h / 70 °C / sealed 2: trifluoroacetic anhydride; pyridine / dichloromethane / 0 - 20 °C View Scheme
参考文献
Bolli, Martin; Lescop, Cyrille; Mathys, Boris; Mueller, Claus; Nayler, Oliver; Steiner, Beat; Velker, Jorg
Patent: US2011/212998 A1, 2011 ;
US 20110212998 A1
反应条件
manganese(IV) oxide in benzene
3 h; Heating / reflux;
参考文献
NIPPON SODA CO., LTD.
Patent: EP1362850 A1, 2003 ;
Location in patent: Page/Page column 33 ;
