(S)-(-)-3-BOC-4-甲氧羰基-2,2-二甲基-1,3-恶唑烷合成路线 (共 17 条)
反应条件
toluene-4-sulfonic acid in benzene 3 h; Ambient temperature;
参考文献
Uchida, Hideharu; Nishida, Atsushi; Nakagawa, Masako
Tetrahedron Letters, 1999 , vol. 40, # 1 p. 113 - 116
反应条件
1: aq. NaHCO3 / tetrahydrofuran / 12 h / 20 °C 2: BF3*Et2O / acetone / 2 h / 20 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 49, # 11 p. 3064 - 3067
反应条件
1: 95 percent / K2CO3 / dimethylformamide / 20 h / 20 °C 2: 92 percent / p-toluenesulfonic acid / toluene / 20 h / Heating View Scheme
参考文献
Organic Letters, , vol. 5, # 23 p. 4253 - 4256
反应条件
in methanol; hexane; benzene T=20°C; 1 h; Inert atmosphere;
参考文献
Lin, Chun-Chieh; Tantisantisom, Worawan; McAlpine, Shelli R.
Organic Letters, 2013 , vol. 15, # 14 p. 3574 - 3577
参考文献
Chun, Jiong; Byun, Hoe-Sup; Arthur, Gilbert; Bittman, Robert
Journal of Organic Chemistry, 2003 , vol. 68, # 2 p. 355 - 359
反应条件
1: 95 percent / Et3N / dioxane; H2O 2: 93 percent 3: 70 percent / H(1+) View Scheme
参考文献
Tetrahedron Letters, , vol. 29, # 25 p. 3037 - 3040
反应条件
1: NaOH 3: 60 percent / p-toluenesulphonic acid View Scheme
参考文献
Tetrahedron Letters, , vol. 25, # 51 p. 5855 - 5858
参考文献
Journal of the Chemical Society - Series Chemical Communications, , # 1 p. 10 - 12
反应条件
diisobutylaluminium hydride in toluene T=-60 - 0°C; 2.5 h;
参考文献
Hu, X. Eric; Kim, Nick K.; Ledoussal, Benoit
Organic Letters, 2002 , vol. 4, # 25 p. 4499 - 4502
反应条件
lithium borohydride in tetrahydrofuran; methanol T=-10°C;
参考文献
Sundermann, Tom; Arnsmann, Martina; Schwarzkopf, Julian; Hanekamp, Walburga; Lehr, Matthias
Organic and Biomolecular Chemistry, 2014 , vol. 12, # 23 p. 4021 - 4030