Multi-step reaction with 2 steps 1: 76 percent / NaI / acetone / 2 h / Heating2: n-BuLi / hexane  

Multi-step reaction with 4 steps 1: 76 percent / NaI / acetone / 2 h / Heating2: n-BuLi / hexane3: 73.2 percent / H2 / 5percent Pd-BaSO4 / pyridine / 8 h / Ambient temperature4: 91 percent / tetrabutylammonium fluoride, 48percent aq. HF / pyridine / 4 h / Ambient temperature  

Multi-step reaction with 6 steps 1: 76 percent / NaI / acetone / 2 h / Heating2: n-BuLi / hexane3: 73.2 percent / H2 / 5percent Pd-BaSO4 / pyridine / 8 h / Ambient temperature4: 91 percent / tetrabutylammonium fluoride, 48percent aq. HF / pyridine / 4 h / Ambient temperature5: 84 percent / Et3N / CH2Cl2 / 1 h / 0 °C6: 80 percent / LiBr / tetrahydrofuran / 14 h / Ambient temperature  

Multi-step reaction with 7 steps 1: 76 percent / NaI / acetone / 2 h / Heating2: n-BuLi / hexane3: 73.2 percent / H2 / 5percent Pd-BaSO4 / pyridine / 8 h / Ambient temperature4: 91 percent / tetrabutylammonium fluoride, 48percent aq. HF / pyridine / 4 h / Ambient temperature5: 84 percent / Et3N / CH2Cl2 / 1 h / 0 °C6: 80 percent / LiBr / tetrahydrofuran / 14 h / Ambient temperature7: 1.) copper(II) sulfate heptahydrate, hydroxylamine hydrochloride, ammonium hydroxyde, 2.) NaCN / 1.) water-ethanol, 5 min, 2.) DMF, r.t., 5 h