5,6,7,8-四氢-4-甲氧基-6-甲基-1,3-二氧杂环戊并[4,5-g]异喹啉-8-醇合成路线 （共 9 条）
反应条件
1: 99 percent / CH2Cl2 / 1 h / Ambient temperature 2: 95 percent / H2 / 5percent Pd-C / ethanol / 7 h / 50 °C 3: I2, potassium acetate / ethanol / 3 h / Heating View Scheme
参考文献
Mao, Yongjun; Song, Shuai; Zhao, Dongmei; Cheng, Maosheng
Heterocycles, 2013 , vol. 87, # 12 p. 2633 - 2640
反应条件
sodium tetrahydroborate; trifluoroacetic acid in dichloromethane
T=0 - 20°C; 25 h;
参考文献
Mao, Yongjun; Song, Shuai; Zhao, Dongmei; Cheng, Maosheng
Heterocycles, 2013 , vol. 87, # 12 p. 2633 - 2640
反应条件
Multi-step reaction with 4 steps 1: 99 percent / CH2Cl2 / 1 h / Ambient temperature2: 95 percent / H2 / 5percent Pd-C / ethanol / 7 h / 50 °C3: I2, potassium acetate / ethanol / 3 h / Heating4: 25percent NaOH, sodium sulfite / H2O / 1) 1h, 40 deg C, 2) 1h, 20 deg C
参考文献
Shirasaka, Tadashi; Takuma, Yuki; Shimpuku, Tetsuro; Imaki, Naoshi Journal of Organic Chemistry, 1990 , vol. 55, # 12 p. 3767 - 3771
反应条件
With sodium hydroxide in ethanol; dichloromethane; sulfuric acid; water Show Experimental Procedure
参考文献
Mitsubishi Chemical Industries Limited Patent: US4760145 A1, 1988 ;
反应条件
With sodium hydroxide in ethanol; dichloromethane; sulfuric acid; water Show Experimental Procedure
参考文献
Mitsubishi Chemical Industries Limited Patent: US4769480 A1, 1988 ;
反应条件
With hydrogenchloride in water T=20°C; 24 h;
参考文献
Mao, Yongjun; Song, Shuai; Zhao, Dongmei; Cheng, Maosheng Heterocycles, 2013 , vol. 87, # 12 p. 2633 - 2640
反应条件
Multi-step reaction with 2 steps 1: 99 percent / H2 / 5percent Pd-C / ethanol2: 78 percent / 6N HCl
参考文献
Shirasaka, Tadashi; Takuma, Yuki; Shimpuku, Tetsuro; Imaki, Naoshi Journal of Organic Chemistry, 1990 , vol. 55, # 12 p. 3767 - 3771
反应条件
With hydrogenchloride
参考文献
Shirasaka, Tadashi; Takuma, Yuki; Shimpuku, Tetsuro; Imaki, Naoshi Journal of Organic Chemistry, 1990 , vol. 55, # 12 p. 3767 - 3771
反应条件
With hydrogenchloride
参考文献
Shirasaka, Tadashi; Takuma, Yuki; Shimpuku, Tetsuro; Imaki, Naoshi Journal of Organic Chemistry, 1990 , vol. 55, # 12 p. 3767 - 3771
