4-(2,5-二甲氧基苯基)丁酸合成路线 （共 16 条）
反应条件
triethylsilane; trifluoroacetic acid 0.166667 h;
参考文献
Chen, Chung-Pin; Swenton, John S.
Journal of Organic Chemistry, 1985 , vol. 50, # 23 p. 4569 - 4576
反应条件
hydrogen; palladium on activated charcoal in ethanol 0.333333 h;
参考文献
Salley, John J.; Glennon, Richard A.
Journal of Heterocyclic Chemistry, 1982 , vol. 19, p. 545 - 550
反应条件
1: Zn; HCl / 3-methyl-butan-1-ol View Scheme
参考文献
Yang, Zhen; Cui, Yu Xin; Wong, Henry N. C.; Wang, Ru Ji; Mak, Thomas C. W.; et al.
Tetrahedron, 1992 , vol. 48, # 16 p. 3293 - 3302
反应条件
1: 82 percent / NaH / dimethylsulfoxide; tetrahydrofuran / 1. 0 deg C, 2. room temp., 15 h. 2: 91 percent / H2 / 10percent Pd/C / ethanol / 0.33 h View Scheme
参考文献
Salley, John J.; Glennon, Richard A.
Journal of Heterocyclic Chemistry, 1982 , vol. 19, p. 545 - 550
反应条件
aluminium trichloride 2.) Wolf Kishner reduction; Yield given. Multistep reaction;
参考文献
Gupta, Dahmendra N.; Hodge, Philip; Hurley, Peter N.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1989 , p. 391 - 394
反应条件
PPA T=80°C; cyclocondensation; 0.5 h;
参考文献
Wipf, Peter; Jung, Jae-Kyu
Journal of Organic Chemistry, 2000 , vol. 65, # 20 p. 6319 - 6337
反应条件
boron trifluoride diethyl etherate; benzene
参考文献
Wipf, Peter; Jung, Jae-Kyu
Journal of Organic Chemistry, 2000 , vol. 65, # 20 p. 6319 - 6337
反应条件
1: polyphosphoric acid
2: 92 percent / POCl3 / dimethylformamide / 6 h / 80 °C
4: 48 percent / pyridinium dichromate
View Scheme
参考文献
Reddy, M. Parameswara; Rao, G. S. Krishna
Tetrahedron Letters, 1981 , vol. 22, # 36 p. 3549 - 3550
反应条件
1: 100 percent / Br2 / acetic acid / Ambient temperature
2: 86 percent / polyphosphoric acid / 0.67 h / 75 °C
View Scheme
参考文献
Braun, Manfred
Tetrahedron Letters, 1980 , vol. 21, p. 3871 - 3874
反应条件
1: 100 percent / Br2 / acetic acid / Ambient temperature
2: 86 percent / polyphosphoric acid / 0.67 h / 75 °C
3: NaBH4 / ethanol / Ambient temperature
4: p-toluenesulfonic acid / benzene / 1.5 h / Heating
View Scheme
参考文献
Braun, Manfred
Tetrahedron Letters, 1980 , vol. 21, p. 3871 - 3874
