1: With pyridine; trifluoromethanesulfonic anhydride in acetonitrile T=70 - 75°C; 1.33333 h; 2: With water; ethanolamine in acetonitrile T=10 - 20°C; 5 h;

pyridine in N2; water; acetonitrile

1.1: potassium carbonate / toluene; water / 1 h / 65 °C / |Inert atmosphere 1.2: 2 h / 80 °C 2.1: urea hydrogen peroxide addition compound; phthalic anhydride / ethyl acetate; water / 4 h / 45 °C 3.1: pyridine; trifluoromethanesulfonic anhydride / acetonitrile / 1 h / 70 - 75 °C 3.2: 2 h View Scheme

1.1: urea hydrogen peroxide addition compound; phthalic anhydride / ethyl acetate; water / 4 h / 45 °C 2.1: pyridine; trifluoromethanesulfonic anhydride / acetonitrile / 1 h / 70 - 75 °C 2.2: 2 h View Scheme

1.1: potassium carbonate / toluene; water / 1 h / 65 °C / |Inert atmosphere 1.2: 2 h / 80 °C 2.1: urea hydrogen peroxide addition compound; phthalic anhydride / ethyl acetate; water / 4 h / 45 °C 3.1: pyridine; trifluoromethanesulfonic anhydride / acetonitrile / 1 h / 70 - 75 °C 3.2: 2 h View Scheme

1: triethylamine; 4-(N,N-dimethlyamino)pyridine / toluene / 2 h 2: hydrogenchloride; water / acetonitrile / 40 - 45 °C View Scheme