hydrogenchloride in methanol; water T=60 - 75°C; 4 h; Product distribution / selectivity;

1: trans 4-{2-[4-(2,3-dichlorophenyl)-piperazine-1-yl]-ethyl}-cyclohexylamine dihydrochloride With triethylamine in dichloromethane T=20 - 25°C; 1 h; 2: bis(trichloromethyl) carbonate in dichloromethane T=-10 - -5°C; 1 h; 3: dimethyl amine Product distribution / selectivity;